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RSV vaccine Arexvy approved by TGA for Australians 60 and over

RSV vaccine Arexvy approved by TGA for Australians 60 and over
Contagious respiratory disease can create more serious symptoms in people with low immunity
Respiratory syncytial virus under the microscope

RSV vaccine Arexvy approved by TGA for Australians 60 and over

Contagious respiratory disease can create more serious symptoms in people with low immunity

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A vaccine to combat a highly infectious respiratory disease has been approved for use in Australia.

The Therapeutic Goods Administration has ticked off Arexvy to be used as a respiratory syncytial virus vaccine for Australians aged 60 and over.

RSV is typically associated with young children but more than 25,000 older Australians were diagnosed with the highly infectious disease last year.

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“We know that this is not just a paediatric disease – it’s a disease that affects all ages, particularly those aged 60 plus,” said a Brisbane GP, Anita Sharma.

“Older patients see a decline in their immunity due to a phenomenon called immunosenescence, which means they cannot mount a good immune response when they are exposed to the virus.”

RSV is highly contagious and can cause mild to moderate illness in younger people, with symptoms including a runny nose, sore throat, cough, fever and aches.

Those with low immunity or co-morbidities including diabetes can suffer more serious symptoms resulting in hospitalisation or time in intensive care, according to Sharma.

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But Arexvy, a protein-based vaccine, boosts the immune response in those more vulnerable patients. “Such a vaccine will help reduce the serious outcomes from RSV infections in patients who receive the vaccine,” Sharma said.

Arexvy was the first vaccine approved for use against RSV in the US, with the drug rolled out there May 2023.

The TGA officially approved Arexvy on Monday as the first RSV vaccine in Australia.

The approval is the first step towards it being administered to those aged 60 and over, with the TGA saying more details on supply and cost would be provided.

The Immunisation Foundation of Australia said it was important that older Australians had access vaccines that would protect them from serious illness. “The announcement of a RSV vaccines ... is a success story for medical research,” said one of its directors, Catherine Hughes.

There were 127,944 confirmed cases of RSV in Australia in 2023, according to the federal government’s national notifiable disease surveillance system. More than 64,000 infections were in children aged under five, while 27,440 people aged 60 and over had RSV.

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